发明名称 |
Phenylamide and pyridylamide beta-secretase inhibitors for the treatment of alzheimer's disease |
摘要 |
The present invention is directed to phenylamide and pyridylamide derivative compounds of which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
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申请公布号 |
US2007142634(A1) |
申请公布日期 |
2007.06.21 |
申请号 |
US20040582856 |
申请日期 |
2004.12.15 |
申请人 |
BARROW JAMES C;COBURN CRAIG A;NANTERMET PHILIPPE G;SELNICK HAROLD G;STACHEL SHAWN J;STANTON MATTHEW G;STAUFFER SHAUN R;ZHUANG LINGHANG;DAVIS JENNIFER R |
发明人 |
BARROW JAMES C.;COBURN CRAIG A.;NANTERMET PHILIPPE G.;SELNICK HAROLD G.;STACHEL SHAWN J.;STANTON MATTHEW G.;STAUFFER SHAUN R.;ZHUANG LINGHANG;DAVIS JENNIFER R. |
分类号 |
A61K31/5377;C07D213/72;C07D213/81;C07D401/04;C07D403/02;C07D413/02;C07D417/02 |
主分类号 |
A61K31/5377 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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