发明名称 |
Polysaccharide-staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections |
摘要 |
Immunogenic polysaccharide-protein conjugates having a polysaccharide antigen (or its oligosaccharide fragment representing one or more antigenic epitopes) derived from a nosocomial pathogen conjugated to a staphylococcal surface adhesin carrier protein are used in immunogenic compositions to elicit antibody responses to both the polysaccharide antigen and the staphylococcal surface adhesin carrier protein. Such immunogenic compositions are used to immunize against diseases caused by Staphylococcal aureus, Staphylococcal epidermidis or other nosocomial pathogens.
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申请公布号 |
US2007141077(A1) |
申请公布日期 |
2007.06.21 |
申请号 |
US20060593481 |
申请日期 |
2006.11.07 |
申请人 |
INHIBITEX, INC. |
发明人 |
PAVLIAK VILIAM;BAKER STEVEN M.;PILLAI SUBRAMONIA P.;PATTI JOSEPH M.;PRATER BRADLEY D. |
分类号 |
A61K39/116;A61K39/085;A61K47/48;C07K14/31 |
主分类号 |
A61K39/116 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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