发明名称 |
Crystalline form of 2-{4-['3-(4-chloro-2-fluorophenyl)-4-pyrimidin-4-yl-1h-pyrazol-5-yl]piperidin-1-yl}-2-oxoethanol |
摘要 |
Crystalline form of the p38 kinase inhibitor 2-{4-[3-(4-chloro-2-fluorophenyl)-4-pyrimidin-4-yl-1H-pyra-zol-5-yl]piperidin-1-yl}-2-oxoethanol can be used, is provided. The crystalline form is a hydrated crystalline form. Also provided are combinations and pharmaceutical compositions comprising the crystalline form, process for preparing the crystalline form and for preparing compositions comprising the crystalline form, in methods for the prophylaxis and/or treatment of a p38 kinase-mediated condition comprising administering to a subject a therapeutically effective amount of the crystalline form of 1.
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申请公布号 |
US2007142412(A1) |
申请公布日期 |
2007.06.21 |
申请号 |
US20040583460 |
申请日期 |
2004.12.15 |
申请人 |
SCHARTMAN RICHARD R;HOFFMAN DOUGLAS H |
发明人 |
SCHARTMAN RICHARD R.;HOFFMAN DOUGLAS H. |
分类号 |
A61K31/506;A61K31/495;C07D401/14;C07D403/14 |
主分类号 |
A61K31/506 |
代理机构 |
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地址 |
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