| 摘要 |
N-(3-oxopregna-4,17(20)-dien-21-yl) quaternary salts and the 19-nor derivatives thereof are prepared by alkylation of the appropriate amine with a 21-halopregna-4,17(20)-dien-3-one or a 21-halo-19-norpregna-4,17(20-dien-3-one followed, if necessary, by ion exchange. These quaternary salts display anti-microbial properties, e.g., anti-bacterial, anti-protozoal, anti-fungal, anti-algal and anthelmintic.
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