发明名称 |
METHOD OF DEPROTECTION |
摘要 |
<p>The invention provides a method for the synthesis of an 18F-labelled product comprising deprotected of a protected 18F-labelled compound using a deprotection agent comprising a weak acid and wherein neutralisation and buffering of the deprotected product are carried out by the addition of a neutralisation agent. The deprotected product is buffered in a pH range suitable for subsequent autoclaving and formulation into an injectable radiopharmaceutical.</p> |
申请公布号 |
EP1797029(A1) |
申请公布日期 |
2007.06.20 |
申请号 |
EP20050784549 |
申请日期 |
2005.09.23 |
申请人 |
GE HEALTHCARE LIMITED |
发明人 |
GRIGG, JULIAN;OSBORN, NIGEL |
分类号 |
C07C227/18;C07B59/00;C07C213/08;C07C215/52;C07C227/20;C07C229/36;C07C229/46;C07D239/54;C07D239/553;C07D277/66;C07D401/06;C07H5/02 |
主分类号 |
C07C227/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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