发明名称 POLYCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION POSSESSING PROPERTY OF H3 RECEPTOR ANTAGONIST AND METHOD FOR TREATMENT BY ITS USING
摘要 FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention relates to novel polycyclic compounds of the formula (I): wherein radicals and symbols have values given in the invention claim. Compounds of the formula (I) possess properties of H3 receptors antagonist. Also, invention relates to a pharmaceutical composition containing compounds of the formula (I). Also, invention relates to a method for treatment of disease of group comprising difficulty in nasal breath, obesity, somnolence, narcolepsy, attention deficiency with hyperactivity, Alzheimer's disease and schizophrenia that involves using compounds of the formula (I) and, optionally, in combination of H receptor antagonist. ^ EFFECT: valuable medicinal properties of compound and pharmaceutical composition. ^ 39 cl, 3 tbl, 31 ex
申请公布号 RU2301231(C2) 申请公布日期 2007.06.20
申请号 RU20030114748 申请日期 2001.10.15
申请人 SHERING KORPOREJSHN 发明人 ASLANJAN ROBERT DZH.;SHIKH NENG-JANG;TING POULIN K.;BERLIN MAJKL J.;ROZENBLJUM STJUART B.;MAK KORMIK KEVIN D.;TOM VING K.;BOJS KRISTOFER V.;MANGIARASINA P'ETRO;MUTAKHI MVANGI VA;PIVINSKI DZHON DZH.
分类号 C07D401/14;A61K31/445;A61K31/4523;A61K31/4545;A61K31/4709;A61K31/4725;A61K31/495;A61K31/496;A61K31/497;A61K31/498;A61K31/506;A61K31/5377;A61K45/00;A61P1/00;A61P3/00;A61P3/04;A61P5/00;A61P9/00;A61P11/00;A61P11/02;A61P11/04;A61P25/00;A61P25/06;A61P25/18;A61P25/28;A61P37/08;C07D213/73;C07D401/12;C07D405/14;C07D409/14;C07D413/14;C07D417/14;C07D498/04 主分类号 C07D401/14
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