发明名称 |
Compositions and methods for modulating NH2-terminal Jun Kinase activity |
摘要 |
Disclosed herein are compositions and methods used to modulate a NH<SUB>2</SUB>-terminal Jun Kinase activity. These compositions and methods can be employed to regulate metabolic disorders associated with, for example, insulin such as diabetes. The reduction in NH<SUB>2</SUB>-terminal Jun Kinase activity can lead to the reduction in weight and improve insulin sensitivity.
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申请公布号 |
US7232897(B2) |
申请公布日期 |
2007.06.19 |
申请号 |
US20040475505 |
申请日期 |
2004.05.03 |
申请人 |
HARVARD UNIVERSITY, PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
HOTAMISLIGIL GOKHAN S.;KARIN MICHAEL;CHANG LUFEN |
分类号 |
C07H17/08;A61K31/00;A61K31/675 |
主分类号 |
C07H17/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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