| 摘要 |
The invention relates to a method for cleaning 3-hydroxyamidinophenylalanine derivatives comprising the steps: (a) addition of an aromatic sulphonic acid to a solution of an optionally contaminated 3-hydroxyamidinophenylalanine derivative in order to form a precipitate; (b) separation of the precipitate formed in step (a); and (c) recovery of the free 3-hydroxyamidinophenylalanine derivative from the precipitate. 3-hydroxyamidinophenylalanine derivatives can e.g. be used as urokinase inhibitors. The invention also relates to the use of highly pure 3-hydroxyamidinophenylalanine derivatives for producing 3-amidinophenylalanine derivatives.
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