USE OF 5HT4 RECEPTOR ANTAGONIST IN MANUFACTURE OF MEDICAMENT FOR PROPHYLAXIS OR TREATMENT OF ATRIAL FIBRILLATION

摘要

PROBLEM TO BE SOLVED: To provide a medicament for the prophylaxis or treatment of heart diseases in a mammal. SOLUTION: The invention relates to the pharmaceutical composition for oral administration of a tablet, a troche agent or a lozenges agent or encapsulated in a hard gelatin capsule as powder or a pellet form containing 50-120 mg (measured as a free base) of a N-[(1-n-butyl-4-piperidinyl) methyl]-3,4-dihydro-2H-[1, 3]oxazino[3, 2-a]indole-10-carboxamide (SB207266) or a pharmaceutically acceptable salt thereof and pharmaceutically acceptable carriers. COPYRIGHT: (C)2007,JPO&INPIT