发明名称 |
PROCESS TO PREPARE SUBSTITUTED IMIDAZOPYRAZINE COMPOUNDS |
摘要 |
<p>A method of preparing formula (A) ,wherein, X=C1, Br, I, comprises the step of treating formula (B), with N-chloro-, N-bromo-, or N-iodosuccinimide in a compatible solvent such as dimethylformamide (DMF) at 0-60° C followed by halogenation.</p> |
申请公布号 |
WO2007067709(A1) |
申请公布日期 |
2007.06.14 |
申请号 |
WO2006US46764 |
申请日期 |
2006.12.07 |
申请人 |
OSI PHARMACEUTICALS, INC.;MULVIHILL, KRISTEN, MICHELLE;CASTELHANO, ARLINDO, L. |
发明人 |
MULVIHILL, KRISTEN, MICHELLE;CASTELHANO, ARLINDO, L. |
分类号 |
C07D487/04 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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