SUSTAINED DELIVERY OF PDGF USING SELF-ASSEMBLING PEPTIDE NANOFIBERS
摘要
The present invention is directed to a therapeutic composition in which human PDGF is bound directly to peptides that self assemble into a biologically compatible gel. When implanted in a patient's body, the composition provides for the slow, sustained release of PDGF. The composition will be especially useful in treating patients who have undergone a myocardial infarction.
申请公布号
WO2006073889(A3)
申请公布日期
2007.06.14
申请号
WO2005US46768
申请日期
2005.12.29
申请人
THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;LEE, RICHARD, T.;HSIEH, PATRICK