发明名称 |
Interaction inhibitors, method of detecting interaction inhibitor and kit detecting interaction inhibitor |
摘要 |
The task is to provide protein interaction inhibitors and/or detection method for interaction inhibitors related to regulation of T cell activation and production of IL-2. The present invention provides inhibitors of interaction between PKC theta and KPNA1, and inhibitors of interaction between KPNA1 and NF-kappaB. Inhibitors of interaction is defined as an candidate compound demonstrating the inhibition of interaction by assaying whether interaction has occurred or not between 2 types of protein and the candidate compound under the conditions allowing interaction of each combination. The detection kit is equipped with samples providing proteins of combinations to be interacted.
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申请公布号 |
US2007134663(A1) |
申请公布日期 |
2007.06.14 |
申请号 |
US20040568578 |
申请日期 |
2004.08.13 |
申请人 |
CELESTAR LEXICO-SCIENCES, INC. |
发明人 |
HIHARA SATOSHI;DOI HIROFUMI |
分类号 |
C12Q1/68;C12N9/99;C12Q1/48;G01N33/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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地址 |
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