A METHOD FOR THE INACTIVATION AND REMOVAL OF DENGUE VIRUS FROM BIOLOGICAL SAMPLES

摘要

A method for inactivating and removing dengue virus from a biological sample comprising the dengue virus and at least one biomolecule of interest, wherein a solvent treatment step is used to inactivate the dengue virus, then a cation exchange chromatography step effectively removes the dengue virus by physically separating it from the biomolecule of interest. In another aspect of the present invention, a method is provided for producing human plasma albumin that is substantially free from infective dengue virus.