Fusion proteins of transferrin and natriuretic peptides with increased serum half-life or serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, binding to iron and/or binding to the transferrin receptor.
申请公布号
WO2007047504(A3)
申请公布日期
2007.06.14
申请号
WO2006US40207
申请日期
2006.10.16
申请人
BIOREXIS PHARMACEUTICAL CORPORATION;SADEGHI, HOMAYOUN;TURNER, ANDREW, J.;PRIOR, CHRISTOPHER, P.;BALLANCE, DAVID, J.
发明人
SADEGHI, HOMAYOUN;TURNER, ANDREW, J.;PRIOR, CHRISTOPHER, P.;BALLANCE, DAVID, J.
