M1 AND/OR M3 RECEPTOR ANTAGONISTS IN COMBINATION WITH OTHER ACTIVES FOR TREATING RESPIRATORY DISORDERS.

摘要

The present invention relates to formulations useful for treating respiratory disorders associated with the production of mucus glycoprotein, skin disorders, and allergic conjunctivitis while substantially reducing adverse effects associated with the administration of non-selective anti-cholinergic agents and methods of use thereof. In particular, the formulations include a selective muscarinic acetylcholdine receptor subtype M1 and/or M3 antagonist such as oxybutynin in combination with one or more pharmaceutically active agents, such as desloratidine.