LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT

摘要

According to the invention, a compound represented by the formula (I) (wherein A represents an aryl group or a monocyclic or dicyclic heterocyclic group, R₁ represents a halide, a nitro group, a substituted C_1-6 alkyl group, an amino group which may be substituted, a C_1-6 alkyloxycarbonyl group, an aryl group which may be substituted, a heterocyclic group or a heterocyclic carbonyl group, R₂ represents a hydrogen atom or a C_1-6 alkyl group, R₃ represents a C_1-6 alkyl group, R₄, R₅ and R₆ each represent a hydrogen atom, R₇ represents a C_1-6 alkyl group, m represents 1 or 2 and n represents 1) or a pharmacologically acceptable salt thereof or a solvate thereof is provided. This compound is a novel lincomycin derivative having a strong activity against resistant pneumococcal strains. Further, this compound can be used as an antibacterial agent and is useful for preventing or treating bacterial infection. (I)