| 摘要 |
The present invention relates to methods and constructs for delivering double stranded RNA (dsRNA) to pest organisms. More specific, the invention relates to a multidomain RNA molecule consisting of a nucleotide sequence comprising (i) at least one aptamer and (ii) at least one nucleotide sequence of interest forming double-stranded RNA, said double-stranded RNA comprising annealed complementary strands, one of which comprises a nucleotide sequence which is complementary to at least part a pest target nucleotide sequence. The invention further relates to nucleic acids encoding the multidomain RNA molecules and to various uses of the multidomain RNA molecules in agriculture. |
