发明名称 COMPOSITIONS AND METHODS FOR MODULATING OSTEOBLAST CELL DIFFERENTIATION AND BONE GENERATION THROUGH HIF-1a
摘要 <p>The present invention provides a novel screening tool for the determination of compounds capable of promoting bone healing, promoting osteoblast cellular differentiation, improving bone mass or volume, and/or promoting osteogenesis that could be used in the treatment of various bone-loss or bone density decreasing disorders. The present invention also provides a screening tool for the determination of compounds capable of inhibiting osteoblast cellular differentiation, decreasing bone mass or volume, and/or inhibiting osteogenesis. Also provided are compositions and methods for the treatment of various bone- loss or bone density decreasing disorders.</p>
申请公布号 WO2007068003(A2) 申请公布日期 2007.06.14
申请号 WO2006US61883 申请日期 2006.12.11
申请人 THE UAB RESEARCH FOUNDATION;THE GENERAL HOSPITAL CORPORATION;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;CLEMENS, THOMAS, L.;JOHNSON, RANDALL, S.;SCHIPANI, ERNESTINA 发明人 CLEMENS, THOMAS, L.;JOHNSON, RANDALL, S.;SCHIPANI, ERNESTINA
分类号 A61B17/56 主分类号 A61B17/56
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