PROCESS FOR THE SEPARATION OF OPTICAL ISOMERS OF THE COREY LACTONE

摘要

The subject of the present invention is the separation of the optical isomers of the racemic hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one ("Corey-lactone") of formula (I), by liquid chromatography. The laevo-rotatory (-) isomer of the compound of formula (I) is a valuable prostaglandin intermediate.