发明名称 Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
摘要 Process for the synthesis of ivabradine of formula (I): addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof. alpha crystalline form of ivabradine hydrochloride. Medicinal products containing alpha crystalline form of ivabradine hydrochloride, which are useful as bradycardics.
申请公布号 US2007135411(A1) 申请公布日期 2007.06.14
申请号 US20070654719 申请日期 2007.01.18
申请人 LES LABORATOIRES SERVIER 发明人 LERESTIF JEAN-MICHEL;LECOUVE JEAN-PIERRE;SOUVIE JEAN-CLAUDE;BRIGOT DANIEL;HORVATH STEPHANE;AUGUSTE MARIE-NOELLE;DAMIEN GERARD
分类号 A61K31/55;A61P9/00;A61P9/04;A61P9/06;A61P9/10;C07D223/16;C07D233/16 主分类号 A61K31/55
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