| 发明名称 |
MEANS AND METHODS FOR INFLUENCING THE STABILITY OF ANTIBODY PRODUCING CELLS |
| 摘要 |
The invention provides a method for influencing the stability of an antibody producing cell, comprising directly or indirectly influencing the amount of BCL6 and/or Blimp 1 expression product within said antibody producing cell. Stable antibody producing cells and cell lines are also provided, as well as methods for producing antibodies using such cells and/or cell lines. |
| 申请公布号 |
CA2633157(A1) |
申请公布日期 |
2007.06.14 |
| 申请号 |
CA20062633157 |
申请日期 |
2006.12.08 |
| 申请人 |
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM;AIMM THERAPEUTICS |
发明人 |
BEAUMONT, TIM;DIEHL, SEAN ANDREW;SCHEEREN, FERENC ALEXANDER;SPITS, HERGEN |
| 分类号 |
C07K16/00;C12N5/0781;C12N5/10;C12P21/08 |
主分类号 |
C07K16/00 |
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