SUBSTITUTED THIAZOLE DERIVATIVES AND THEIR USES AS TYROSINE KINASE INHIBITORS

摘要

The present invention relates to novel compounds selected from thiazole derivatives that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective c-kit inhibitors.