<p>The invention relates to a tobacco alkaloid patch (10; 41; 42; 43; 51; 52; 53; 54) for transdermal administration of a tobacco alkaloid, said patch comprising an impermeable backing (11) and a membrane (14) which defines a cavity (12) there between, said membrane being permeable to and in contact with said tobacco alkaloid, said impermeable backing and said membrane being at least partly joined by a sealing and wherein the width (17) of said sealing is at least about 1mm. According to the invention an improved low-area tobacco alkaloid patch has been obtained.</p>