发明名称 |
Methods of using molecules related to organic cation transporter 3 (oct3) for treating depression, anxiety neuroses, drug dependencies, and other similar mental disorders |
摘要 |
Mice in which OCT3 expression is suppressed were successfully constructed by administering antisense against OCT3 gene into the brain. Mice in which OCT3 expression is suppressed display phenotypes related to mental disorders such as anti-depression and anti-anxiety, and therefore the mice can be applied to the screening of therapeutic agents for mental disorders. In addition, substances suppressing the OCT3 expression or function were shown to be in fact effective as therapeutic agents for depression and anxiety neuroses.
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申请公布号 |
US2007136828(A1) |
申请公布日期 |
2007.06.14 |
申请号 |
US20060592154D |
申请日期 |
2006.02.24 |
申请人 |
BIOSTATION INC. |
发明人 |
KITAICHI KIYOYUKI |
分类号 |
A01K67/027;A61K31/138;A61K31/7088;A61K31/713;A61K39/395;A61K45/00;A61K45/06;A61K48/00;A61K49/00;A61P25/18;A61P25/22;A61P25/24;A61P25/36;C07K14/47;C07K16/18;C12N15/00;C12N15/113;C12N15/85;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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地址 |
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