| 发明名称 |
Synthesis by chiral diamine-mediated asymmetric alkylation |
| 摘要 |
<p>Chiral synthesis from an achiral starting material by chiral diamine-mediated, such as sparteine-mediated, intermolecular asymmetric alkylation with a strained cyclic ether in the presence of a Lewis acid.</p> |
| 申请公布号 |
EP1794129(A2) |
申请公布日期 |
2007.06.13 |
| 申请号 |
EP20050807777 |
申请日期 |
2005.09.28 |
| 申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
DENG, XIAOHU;MANI, NEELAKANDHA |
| 分类号 |
C07D203/18;C07D205/04;C07D207/08;C07D211/22;C07D221/22;C07D223/04;C07D225/02;C07D401/06 |
主分类号 |
C07D203/18 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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