Cell penetrating peptides for intracellular delivery of molecules

摘要

The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX 9 WRAX 9 WRX 1 LX 2 RSLX 9 WX 3 X 4 X 5 X 6 X 7 X 8 (SEQ ID No: 1), wherein X 1 is A, L or G, X 2 is W or none, X 3 is R or K, X 4 is K, L or S, X 5 is L or K, X 6 is R or W, X 7 is K or S, and X 8 is A, V or Q, and X 9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.