发明名称 ARENE RUTHENIUM (II) COMPOUNDS AND THEIR USE IN CANCER THERAPY
摘要 or a solvate or prodrug thereof, wherein: R1, R1, R3, R4, R5 and R6 are independently selected from H, C1-7 alkyl, C5-20 aryl, C3-20 heterocyclyl, halo, ester, amido, acyl, sulfo, sulfonamido, ether, thioether, azo, amino, or R1 and R2 together with the ring to which they are attached form a saturated or unsaturated carbocyclic or heterocyclic group containing up to three 3- to 8- membered carbocyclic or heterocyclic rings, wherein each carbocyclic or heterocyclic ring may be fused to one or more other carbocyclic or heterocyclic rings; X is a neutral or negatively charged N- or S- donor ligand; Y is a counterion; m is 0 or 1; q is 1, 2 or 3; C' is C1-12 alkylene bound to two A groups; p is 0 or 1 and r is 1 when p is 0 and r is 2 when p is 1; and A and B are each independently O-donor, N-donor or S-donor ligands, and may be connected to one another. The compounds are used in cancer therapy.
申请公布号 KR20070060091(A) 申请公布日期 2007.06.12
申请号 KR20077006364 申请日期 2007.03.20
申请人 THE UNIVERSITY OF COURT OF THE UNIVERSITY OF EDINBURGH 发明人 HABTEMARIAM ABRAHA;SADLER PETER JOHN
分类号 C07F15/00;A61K31/28;A61P35/00 主分类号 C07F15/00
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