ALIPHATIC AMINE POLYMER SALTS FOR TABLETING.

摘要

The tablets, compositions and methods of the present invention, comprising a carbonate salt of an aliphatic amine polymer and s monovalent anion canprevent or ameliorate acidosis, in particular acidosis in patients with renal disease. The tablets and compositions of the present invention maintain a disintegration time of no greater than 30 minutes at 37 C and at pH of at least 1 for a period of at least ten weeks at 60 C. Furthermore, the tablets are stable for extended periods of time without the need for specialized storage conditions.