| 发明名称 |
Amorphous HMG-CoA reductase inhibitors of desired particle size |
| 摘要 |
In one aspect, the invention provides a process for the preparation of an amorphous HMG-CoA reductase inhibitor and hydrates thereof of desired particle size, which comprises: dissolving the HMG-CoA reductase inhibitor in a hydroxylic solvent, and removing the solvent by freeze-drying.
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| 申请公布号 |
US7230120(B2) |
申请公布日期 |
2007.06.12 |
| 申请号 |
US20040483553 |
申请日期 |
2004.01.12 |
| 申请人 |
BIOCON |
发明人 |
POORNAPRAJNA ACHARYA;MATHEW JOY;CHANDRAPPA RAVINDRA;SRIDHARAN MADHAVAN;GANESH SAMBASIVAM |
| 分类号 |
C07D207/335;A61K31/22;A61K31/40;A61P3/06;C07C;C07C51/43;C07C59/62;C07C67/52;C07C69/732;C07D207/34 |
主分类号 |
C07D207/335 |
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