发明名称 |
METHOD OF SELECTING MYOCARDIAL CELLS BY USING INTRACELLULAR MITOCHONDRIA AS INDICATION |
摘要 |
It is intended to develop a method whereby myocardial cells are selected from the whole heart-constituting cells or stem cell-origin differentiated cells without resorting to gene modification. Based on the various properties of myocardial cells, an epoch-making method of selecting myocardial cells by using a mitochondria-specific labeling reagent without resorting to gene modification is established. Namely, a method of selecting myocardial cells from a cell mixture containing the myocardial cells depending on the relative mitochondrial content in the cells or the relative mitochondrial membrane potential of the cells without resorting to gene modification in the myocardial cells; a method of concentrating myocardial cells from a cell mixture containing the myocardial cells without resorting to gene modification in the myocardial cells; a method of producing myocardial cells without resorting to gene modification in the myocardial cells; and a method of estimating the ratio of myocardial cells in a cell mixture containing the myocardial cells. |
申请公布号 |
KR20070057804(A) |
申请公布日期 |
2007.06.07 |
申请号 |
KR20077004065 |
申请日期 |
2005.08.26 |
申请人 |
ASUBIO PHARMA CO., LTD.;KEIO UNIVERSITY |
发明人 |
HATORI FUMIYUKI;FUKUDA KEIICHI |
分类号 |
C12N5/07;C12Q1/06;C12Q1/00;G01N33/48 |
主分类号 |
C12N5/07 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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