发明名称 METHODS OF TREATING EPILEPTOGENESIS AND EPILEPSY
摘要 This invention is directed to methods for preventing, treating, reversing, inhibiting or arresting epilepsy and epileptogenesis in a subject comprising administering to the subject in need thereof a therapeutically effective amount of a compound selected from the group consisting of Formula (I) and Formula (II), or a pharmaceutically acceptable salt or ester thereof,: Formula (I) Formula (II) wherein phenyl is substituted at X with one to five halogen atoms selected from the group consisting of fluorine, chlorine, bromine and iodine; and, R1, R2, R3, R4, R5 and R6 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
申请公布号 KR20070057939(A) 申请公布日期 2007.06.07
申请号 KR20077008402 申请日期 2007.04.13
申请人 JANSSEN PHARMACEUTICA N. V 发明人 CHOI, YONG MOON;GORDON ROBERT;NOVAK GERALD P.;PLATA SALAMAN CARLOS R.;TWYMAN ROY E.;WHITE H. STEVE;ZHAO BOYU
分类号 A61K31/27;A61K31/325;A61P25/08 主分类号 A61K31/27
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