| 发明名称 |
Neuregulin variants and methods of screening and using thereof |
| 摘要 |
The present invention provides polypeptide variants of neuregulin-1beta (NRG-1beta) that have enhanced or decreased binding affinity to ErbB3 and/or ErbB4. The invention also provides methods of screening and producing polypeptide variants of NRG-1beta and methods of using polypeptide variants of NRG-1beta for treating diseases. |
| 申请公布号 |
AU2006319620(A1) |
申请公布日期 |
2007.06.07 |
| 申请号 |
AU20060319620 |
申请日期 |
2006.12.04 |
| 申请人 |
ZENSUN (SHANGHAI) SCIENCE & TECHNOLOGY LIMITED |
发明人 |
MINGDONG ZHOU |
| 分类号 |
C07K14/435;A61K38/17;A61P9/00;A61P25/18;A61P31/12;C12N15/12;G01N33/68 |
主分类号 |
C07K14/435 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
