发明名称 MEASURING METHOD OF INTERACTION WITH BIOMOLECULE
摘要 PROBLEM TO BE SOLVED: To provide a measuring method applicable to an automatic analyzer, capable of accurately, quickly and simply measuring with excellent reproducibility, an interaction between a biomolecule and a molecule interacting with calcium ions and having a structure changed according to the concentration of the calcium ions. SOLUTION: This measuring method of the interaction between the biomolecule and the molecule interacting with calcium ion, and having a structure changed according to the concentration of the calcium ions is characterized by including: a process for performing fluorescence labeling of the molecule interacting with calcium ions, having a structure changed according to the concentration of the calcium ions; a process for mixing the fluorescence-labeled molecule with the biomolecule; a process for measuring fluctuation of the fluorescence; and a process for detecting the interaction between the biomolecule and the molecule having a changing structure by analyzing a measurement result of the fluctuation of the fluorescence. COPYRIGHT: (C)2007,JPO&INPIT
申请公布号 JP2007139663(A) 申请公布日期 2007.06.07
申请号 JP20050336164 申请日期 2005.11.21
申请人 OLYMPUS CORP;GIFU UNIV 发明人 KOBAYASHI SAYOKO;NISHIKAWA KAZUYA;YOKOGAWA TAKASHI;ONO SATOSHI;OKAMOTO NAOAKI
分类号 G01N33/543;C12N15/09;G01N21/78;G01N33/84 主分类号 G01N33/543
代理机构 代理人
主权项
地址