发明名称 Tricyclic hydroxamate and benzamide derivatives, compositions and methods
摘要 The present invention relates to compounds and methods for inhibiting histone deacetylase enzymatic activity. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit histone deacetylases (IIDACs), and in the treatment of conditions mediated by HDAC, cancer, proliferative conditions, psoriasis, and also central nervous system diseases. It further deals with processes for preparing said compounds.
申请公布号 US2007129368(A1) 申请公布日期 2007.06.07
申请号 US20040581947 申请日期 2004.12.10
申请人 LEBLOND BERTRAND;BEAUSOLEIL ERIC 发明人 LEBLOND BERTRAND;BEAUSOLEIL ERIC
分类号 A61K31/53;A61K31/353;A61K31/382;A61K31/416;A61K31/4178;A61K31/423;A61K31/427;A61K31/4709;A61K31/506;C07C233/80;C07C259/06;C07C259/10 主分类号 A61K31/53
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