CARBONIC ANHYDRASE IX (G250) ANTIBODIES AND METHODS OF USE THEREOF
摘要
The invention provides scFv antibodies and monoclonal antibodies that bind to and decrease an activity of Carbonic Anhydrase IX (G250). Also provided are methods of treating and/or preventing cancer, such as renal clear cell cancer. Also provided are methods of identifying a carbonic anhydrase IX (G250) protein. The invention additionally provides methods of modifying immune effector cells, and the immune effector cells modified thereby.
申请公布号
WO2007065027(A2)
申请公布日期
2007.06.07
申请号
WO2006US46350
申请日期
2006.12.04
申请人
DANA FARBER CANCER INSTITUTE;MARASCO, WAYNE, A.;LO, AGNES;XU, CHEN