发明名称 |
PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN LABELED ORGANIC COMPOUND |
摘要 |
It is intended to provide a novel amino acid organic compound which can be used as a labeling precursor compound for radioactive halogen-labeled amino acid compounds including [ 18 F]FACBC, and which prevents methanol from remaining in the radioactive halogen-labeled amino acid compounds produced therefrom. The novel amino acid organic compound is a compound represented by the following formula:
wherein n is an integer of 0 or of 1 to 4; R 1 is an ethyl, 1-propyl or isopropyl substituent; X is a halogen substituent or a group represented by -OR 2 ; R 2 is a straight-chain or branched-chain haloalkylsulfonic acid substituent with one to 10 carbon atoms, trialkylstannyl substituent with 3 to 12 carbon atoms, fluorosulfonic acid substituent or aromatic sulfonic acid substituent; and R 3 is a protective group. |
申请公布号 |
CA2629227(A1) |
申请公布日期 |
2007.06.07 |
申请号 |
CA20062629227 |
申请日期 |
2006.11.28 |
申请人 |
NIHON MEDI-PHYSICS CO., LTD. |
发明人 |
SHINMURA, TOSHIYUKI;HARANO, ARINORI;KUROSAKI, FUMIE;TOYAMA, MASAHITO;ITO, OSAMU;HAYASHI, AKIO |
分类号 |
C07C309/65;A61K49/00;C07B59/00 |
主分类号 |
C07C309/65 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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