METHODS AND COMPOSITIONS TO IMPROVE ACTIVITY AND REDUCE TOXICITY OF STENTS
摘要
<p>Disclosed is a method of improving the efficacy of endovascular drug- releasing stents implanted in a subject, wherein one or more modulators of drug transport are administered at such a time as is beneficial to maintain nearby tissue concentrations of the drug released by the stent within their therapeutically effective range, wherein one or more modulators of drug activity are administered at such a time as is beneficial to prevent restenosis, and wherein one or more modulators of drug activity are administered at such a time as is beneficial to promote the early healing or reendothelialization process.</p>
