ANTIARRHYTMIC MEDICAMENTS WITH PROLONGED ACTION OF WHICH THE ACTIVE PRINCIPLE IS A-(2-(BIS(1-METHYLETHYL)AMINO)ETHYL)-A-PHENYL-2-PYRIDINE-ACETAMIDE OR ONE OF ITS SALTS,THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM

摘要

Antiarrhythmic sustained release pharmaceutical compositions for oral administration comprise: (a) a-Ä2-Äbis-(1-methylethyl)aminoÜethylÜ- a-phenyl-2-pyridine acetamide or a pharmaceutically acceptable addition salt thereof with a mineral or organic acid, (b) an ester of glycerin and of a fatty acid containing from 10 to 22 carbon atoms, (c) an inert material having a solubility in water at ambient temperature of from 0.2 g to 3 g per millilitre.