发明名称 |
Fremgangsmåde til fremstilling af vacciner til forebyggelse af de patogene virkninger relateret til en HIV-retrovirusinfektion |
摘要 |
<p>The invention provides a method of searching for and obtaining a vaccine against the pathogenic effects related to the infection of an animal or human host by a retrovirus that penetrates into a target cell of the host, and a vaccine obtained by the method are provided. The method includes preparing candidate vaccine agents based on a polypeptide comprising at least part of an envelope protein of a pathogenic strain of the retrovirus and selecting as the vaccine a modified polypeptide chosen from polypeptides that induces an immune response directed against an immunodominant region of an envelope protein of the retrovirus and not against a protein of the host.</p> |
申请公布号 |
DK1034000(T3) |
申请公布日期 |
2007.06.04 |
申请号 |
DK19980955673T |
申请日期 |
1998.11.17 |
申请人 |
MYMETICS SA |
发明人 |
SERRES, PIERRE-FRANCOIS;GEOURJON, CHRISTOPHE;DELEAGE, GILBERT;COMBET, CHRISTOPHE |
分类号 |
A61K39/21;C12N15/09;A61K39/00;A61P31/14;A61P31/18;A61P35/00;A61P37/04;C07K14/155;C07K14/16;C07K16/10;C07K16/22;C07K16/24;C07K16/26;C12N5/02;C12N7/01;C12N15/48 |
主分类号 |
A61K39/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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