Process for preparing 4-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives

摘要

The invention relates to processes for preparing compounds of formula 1 wherein R<3> is as defined herein, and to pharmaceutically acceptable salts thereof, as well as intermediates useful in such processes. The compounds of formula 1 are antibacterial agents that may be used to treat various bacterial and protozoa infections. The invention also relates to pharmaceutical compositions containing compounds prepared by the processes of the invention and to methods of treating bacterial protozoa infections by administering such compounds.