| 发明名称 |
N-(3,3-DIMETHYLINDOLIN-6-YL){2-[(4-PYRIDYLMETHYL)AMINO}(3-PYRIDYL)}CARBOXAMIDE AND PHARMACEUTICAL COMPOSITIONS THEREOF. |
| 摘要 |
Selected heterocyclic compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes. |
| 申请公布号 |
PT1358184(E) |
申请公布日期 |
2007.05.31 |
| 申请号 |
PT20020717325T |
申请日期 |
2002.01.11 |
| 申请人 |
AMGEN, INC. |
发明人 |
JEAN BEMIS;ALEXANDER KISELYOV;CELIA DOMINGUEZ;GUOQING CHEN;JEFFREY ADAMS;SHON BOOKER;GUOLIN CAI;MICHAEL CROGHAN;LUCIAN DIPIETRO;DANIEL ELBAUM;JULIE GERMAIN;STEPHANIE GEUNS-MEYER;MICHAEL HANDLEY;QI HUANG;JOSEPH, L. KIM;TAE-SEONG KIM;XIAOHU OUYANG;VINOD F. PATEL;LEON M. SMITH;MARKIAN STEC;ANDREW TASKER;NING XI;SHIMIN XU;CHESTER CHENGUANG YUAN |
| 分类号 |
C07D401/14;A61K31/4436;A61K31/444;A61K31/4709;A61K31/496;A61K31/501;A61K31/506;A61K31/5377;A61P9/10;A61P11/06;A61P15/08;A61P17/06;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07D213/82;C07D401/12;C07D405/12;C07D405/14;C07D407/14;C07D409/04;C07D409/12;C07D409/14;C07D413/14;C07D417/14;C07D471/04 |
主分类号 |
C07D401/14 |
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