发明名称 DNA CONSTRUCTS FOR SPECIFIC INHIBITION OF GENE EXPRESSION BYRNA INTERFERENCE
摘要 <p num="1"><br/><br/><br/>The invention relates to expression constructs and methods for their <br/>production which are suitable, after transfection thereof into eukaryotic <br/>cells, for inhibiting in a targeted manner in these cells the formation of <br/>defined proteins by RNA interference. Methods for producing such vectors <br/>contain no PCR steps, are a three-step procedure in one reaction vessel and <br/>can be carried out within a few hours. In addition, DNA expression constructs <br/>which are suitable for targeted inhibition of gene expression by means of RNA <br/>interference are, in addition, subject matter of the invention, wherein these <br/>are expression constructs which are also suitable for multiple gene expression <br/>inhibition.<br/>
申请公布号 CA2627443(A1) 申请公布日期 2007.05.31
申请号 CA20062627443 申请日期 2006.11.22
申请人 MOLOGEN AG 发明人 SCHROFF, MATTHIAS;OSWLAD, DETLEF
分类号 C12N15/11;C12N15/113 主分类号 C12N15/11
代理机构 代理人
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