RECOMBINANT POLYVALENT VACCINE

摘要

Disclosed are recombinant varicella-zoster virus, a process for producing the virus, a pharmaceutical composition comprising the recombinant varicella-zoster virus, a vector having a BAC vector sequence in a specific gene of the varicella-zoster virus genomic gene, a cell having the vector therein, a fragment capable of homologous recombination with the varicella-zoster virus genome, a nucleic acid cassette comprising a BAC vector sequence, and a polyvalent vaccine. A process for producing a recombinant varicella-zoster virus having a BAC vector sequence inserted in a specific viral gene.