Aerosol formulation for inhalation comprising a tiotropium salt

摘要

Pharmaceutical preparation consisting of: tiotropium bromide as active substance, in a concentration based on tiotropium cation of between 0.02 g per 100 ml of formulation and 0.05 g per 100 ml of formulation, the tiotropium bromide being present in the pharmaceutical preparation in totally dissolved form water as the only solvent, acid for adjusting the pH to between 2.7 and 3.1, benzalkonium chloride in an amount of between 8 mg / 100 ml of formulation and 12 mg /100 ml of formulation, sodium edetate in an amount of between 8 mg / 100 ml of formulation and 12 mg / 100 ml of formulation. Pharmaceutical preparations of the type described are particularly suitable for nebulising the active substance using an atomiser for administration by inhalation.