发明名称 |
New sulfamoylsulfonate prodrugs e.g. useful for protecting red blood cells from attack by parasites or for hormone replacement therapy, female fertility control or treating hormone-associated diseases |
摘要 |
<p>Sulfamoylsulfonate prodrugs (I) are new. Sulfamoylsulfonate prodrugs of formula (I) are new. Drug-O-SO 2-X-SO 2NH 2 (I) X : 1-12C alkanediyl, 1-5C perfluoroalkylene, 3-8C cyloalkanediyl, arylene, heteroalkanediyl, 1-4C alkanediylaryl, (1-4C)alkanediyl(3-8C)cycloalkyl or (3-8C)cycloalkanediyl(1-4C)alkyl; Drug : a pharmaceutical agent capable of forming a sulfonate through an OH group. Independent claims are also included for: (1) pharmaceutical composition comprising a prodrug (I) and another active agent; (2) a process for preparing (I). ACTIVITY : Antiparasitic; Protozoacide; Gynecological; Cytostatic; Antiinflammatory; Antiallergic. MECHANISM OF ACTION : None given.</p> |
申请公布号 |
DE102005057408(A1) |
申请公布日期 |
2007.05.31 |
申请号 |
DE20051057408 |
申请日期 |
2005.11.30 |
申请人 |
BAYER SCHERING PHARMA AG |
发明人 |
WYRWA, RALF;NUBBEMEYER, REINHARD;GANZER, URSULA |
分类号 |
C07J31/00;A61K31/59;A61P37/08 |
主分类号 |
C07J31/00 |
代理机构 |
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