Fermentative preparation of organic compounds, useful for making e.g. amino acids or enzymes, comprises using a starch source from which non-starch solids have not been removed, hydrolyzed and mixed with sugars

摘要

Preparation of at least one organic compound (I) with at least 3 C atoms or at least two C and at least one N by fermentation. Preparation of at least one organic compound (I) with at least 3 C atoms or at least two C and at least one N by fermentation comprises: (a) millling a starch source (S) to form a milled product (MP) that contains at least part of the non-starch-containing solid components (X) of (S); (b) suspending (MP) in an aqueous liquid and hydrolysis of the starch components by enzymatic liquefaction and optionally subsequent saccharification, to form a first liquid medium (1), containing mono- or oligo-saccharides; and (c) adding (1), together with metabolizable mono-, di- and/or oligo-saccharides (Y), or compositions containing at least 50wt.% (Y) essentially free of water-insoluble solids, to a fermentation medium that contains microorganisms (MO) which can overproduce (I), under fermentation conditions.