| 摘要 |
Disclosed are compounds of formula I and processes of preparing them wherein: X-Y is -CH2-CH2-, -CH=CH- or -CH2O-; R1, R1.1 and R1.2 independently from each other are selected from the group consisting of H, halogen, cyano, alkyl, halogen-alkyl, alkoxy or halogen-alkoxy; R21, R22 and R23 independently from each other are selected from the group consisting of H and halogen; R24 is H, halogen or methyl; R3 is H; R4 is -CONHR5, -CH or -NHR6; R5 is H or alkyl; and R6 is -CO-H, -CO-alkyl, -CO-halogen-alkyl, -CO-O-alkyl, -CO-NH2 or -SO2-alkyl. Compounds of the type disclosed are monoamine oxidase B (MOAB) inhibitors useful in the treatment of diseases such as Alzheimer's disease and senile dementia.
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