Novel analogues and derivatives of novobiocin are provided, including compounds having modifications to the amide side chain, coumarin ring, and sugar moieties. The compounds of the present invention are useful as heat shock protein 90 inhibitors, and may be used as anticancer and neuroprotective agents.
申请公布号
WO2006050501(A3)
申请公布日期
2007.05.31
申请号
WO2005US39990
申请日期
2005.11.03
申请人
UNIVERSITY OF KANSAS;DEPARTMENT OF HEALTH AND HUMAN SERVICES;BLAGG, BRIAN, S.;NECKERS, LEN;YU, XIAO, MING
