PROCESS FOR PRODUCTION OF FUCOXANTHINOL

摘要

[PROBLEMS] To provide a process which can produce fucoxanthinol within a short time, at low cost and with high efficiency. [MEANS FOR SOLVING PROBLEMS] A process for production of fucoxanthinol comprises: a first step in which fucoxanthin (0.5 g) is dissolved in methanol (300 mL) and a surfactant sodium taurocholate (2.5 g) is then added and dissolved to the resulting solution; a second step in which the solution of fucoxanthin and sodium taurocholate in methanol prepared in the first step is evaporated to dryness; a third step in which the resulting dry material is dissolved in a potassium phosphate buffer (0.1 M; pH=7.0; 500 mL), a porcine pancreas-derived lipase (10 g) is added to the solution, and the resulting mixed solution is incubated at 37°C for 2 hours; and a forth step in which fucoxanthinol thus produced is purified by column chromatography. The process can produce fucoxanthinol having high purity in a large amount, at low cost, and within a short time.