发明名称 |
METHODS AND COMPOSITIONS FOR TREATING DISEASES TARGETING HUMAN PROMININ-1(CD133) |
摘要 |
<p>Methods and compositions for detecting and treating diseases, especially cancer, and particularly breast, bladder, colon, gastrointestinal, kidney, liver, lung, melanoma, ovary, pancreatic, pharyngeal, prostate cancer and renal, associated with differential expression of prominin-1 (CD133) in disease cells compared to healthy cells. Also provided are antagonists or agonists of prominin-1, and methods for screening agents that modulate the prominin-1 level or activity in vivo or in vitro.</p> |
申请公布号 |
WO2007062138(A2) |
申请公布日期 |
2007.05.31 |
申请号 |
WO2006US45237 |
申请日期 |
2006.11.22 |
申请人 |
APPLERA CORPORATION;SEATTLE GENETICS, INC.;VAN ORDEN, KAREN;SMITH, MARIA, LEIA;NESTEROVA, ALBINA;LEE, CANDY;DOMON, BRUNO;RUBEN, STEVE |
发明人 |
VAN ORDEN, KAREN;SMITH, MARIA, LEIA;NESTEROVA, ALBINA;LEE, CANDY;DOMON, BRUNO;RUBEN, STEVE |
分类号 |
G01N33/53 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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